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When "stoped clozaril to fast brain damage" ulcers are situated in the rectum or sigmoid region they are readily demonstrable with the aid of the enteroscope.

Addison characterized a group of cases by a"general anaemia occurring without any discoverable cause whatever, cases in which there had been no previous loss of blood, no exhausting diarrhoea, no chlorosis, no purpura, no renal, splenic, miasmatic, glandular, strumous or malignant disease." According to one theory these cases are due to increased haemolysis excited by absorption of poisons from the intestines and elsewhere, on the other hand other authorities believe it is due to defective haemogenesis.

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